Study: Monkeypox Virus Infection Resulting from an Occupational Needlestick — Florida, 2022. Image Credit: Dotted Yeti/Shutterstock

The CDC advises protocols for collecting monkeypox specimens after an exposure case in the United States

A recent report published in the United States (US) Centers for Disease Control and Prevention (CDC) Weekly morbidity and mortality report Describe a case of occupational exposure to monkeypox. They commented on the Centers for Disease Control and Prevention’s advisory advice on collecting swabs for testing for monkeypox.

Stady: Monkeypox virus infection caused by an occupational needle needle – Florida, 2022. Image Credit: Dotted Yeti / Shutterstock

occupational exposure accident

The report described a case in which a Florida emergency department nurse was exposed to monkeypox virus through a needlestick injury while collecting swab samples from a suspected monkeypox patient. A needle was used to open a skin lesion to obtain a swab sample of the lesion’s fluid. The injury occurred while the nurse was putting the cap back on the used needle before disposal. The needle pierced the skin of the nurse’s finger through the glove, causing slight bleeding. Immediate measures were taken to wash and disinfect the area with soap and water and a 10% povidone-iodine solution.

Swabs from the patient were analyzed using real-time polymerase chain reaction (rtPCR) and tested positive for West African monkeypox virus Clade II. The nurse was given the first dose of JYNNEOS vaccine as post-exposure prophylaxis within 15 hours of exposure and was monitored by the county health department and an infectious disease specialist at the hospital.

A skin lesion appeared at the site of injury ten days after exposure. The lesion was swabbed and tested with PCR, and multiple smears were tested positive for nonpox Orthopox The monkeypox virus. The lesion grew over the next 19 days. It became deep-seated, developed a depression in the middle, and formed pus. Eventually the lesion clumps and new skin grows under the crust. The nurse did not have any other clinical lesions or symptoms, and no OrthopoxAntiviral medicines such as tekovirimat were given. Furthermore, no secondary cases of this exposure have been demonstrated.

CDC استشاري Consultant

The CDC recommends not opening or inhaling monkeypox skin lesions with sharp instruments such as needles to obtain swab samples to avoid injuries while redrawing or handling the instruments.

Data from monkeypox testing during the 2022 outbreak in the US revealed that swabs samples taken from skin and mucosal lesions indicated very low cycle-cycle values ​​during qPCR, indicating that sufficient viral material was obtained for conclusive testing without the need for Remove skin lesions. A thorough survey of the lesion surface provides sufficient samples to obtain reliable test results, avoiding the risks of injury and accidental exposure.

The CDC has also advised health care departments to ensure that health care workers are adequately trained in sample collection methods and infection prevention protocols while caring for a patient with monkeypox. Furthermore, if sharps are used during other patient care procedures, the CDC recommends that health care professionals implement strict procedures for the safe disposal of sharps.

In addition, health care workers with known exposures should be tested and given post-exposure prophylactic treatments immediately.


To summarize, the current CDC advisory recommended that the skin lesions of monkeypox patients are not untied or inhaled to obtain swab samples after a case of accidental occupational exposure to the virus through a needlestick injury.

The CDC states that swab samples from the skin of lesions provide sufficient viral material for a reliable positive qPCR test without the need to open the lesions.

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