Screening of patients at risk of syphilis, staff advises

Screening of patients at risk of syphilis, staff advises

The recommendationpublished on September 27 with the extension Grade “A”along with Final Evidence Review And the Evidence summaryreaffirms 2016 guidance separate recommendation Published in 2018 calls for early screening for syphilis in pregnant patients.

Family physician Katrina Donahue, a staff member and professor and vice chair of research in the Department of Family Medicine at the University of North Carolina School of Medicine at Chapel Hill, explained in USPSTF Bulletin. “In the face of rising rates of syphilis, primary care professionals play an important role in helping to keep their patients healthy.”

Reported syphilis cases have increased steadily in the United States over the past two decades, from 2.1 cases per 100,000 people in 2000 to me 11.9 cases per 100,000 in 2019. While syphilis is easily treatable if diagnosed early, it can cause blindness, paralysis, nervous system damage, and other problems if left untreated.

The accuracy of the test varies according to the stage of the disease

Because the USPSTF has previously determined that treatments for syphilis (eg parenteral penicillin G) are effective and well established, the treatments were not included in the evidence review. Instead, the task force investigated whether there was enough new and substantive evidence to change the 2016 recommendation, focusing on risk assessment tools and the benefits and harms of screening.

The investigators found that the accuracy of the test can vary based on the stage of the disease. For detection of primary and late latent syphilis, common non-treponemal tests had a sensitivity of between 61% and 78% for detecting primary and late latent syphilis, and between 85% and 100% for detecting secondary and early latent syphilis. Preferred treponemal tests (which detect antibodies to T. pallidum proteins) showed better sensitivity (82% to 100%) across the disease spectrum and better specificity (94% to 100%) for detecting primary syphilis.

Rapid point-of-care test for T. pallidum Antibodies can provide rapid in situ results, but realistic preliminary data suggest sensitivity may be low.

Although the researchers found that screening of patients at risk for syphilis was the standard of care in the United States, they recognized the need for more research on a variety of related topics, including

  • new testing methods,
  • The best way to determine who will benefit most from screening and
  • Optimal examination periods.

Recommendations and other resources

In response to comments made on the draft version of the recommendation between February 15, 2022 and March 14, 2022, the final recommendation includes more information on factors that cause discrepancies in the prevalence of syphilis among different patient groups, preferred screening tests, and test performance of screening tests different and additional risk factors.

Connect staff to three new resources for clinicians and patients, including a Consensus Report of the National Academies of Sciences, Engineering, and Medicine On sexually transmitted diseases, a gamma patient page On screening for syphilis and a gamma audio notation on the statement of recommendation.

The task force has also published screening recommendations for several other STIs, including chlamydia and gonorrhea, genital herpes, hepatitis b, hepatitis C And the human immunodeficiency virus, As well as a recommendation on behavioral counseling For all sexually active teens and adults at risk of infection.

#Screening #patients #risk #syphilis #staff #advises

Leave a Comment

Your email address will not be published. Required fields are marked *