CV – Founded in Salt Lake City, Utah earlier this year– will submit ONEGO BIOStress engineering, bioprocess development, regulatory support, and process services expansion as Onego Bio attempts to commercialize animal-free ovalbumin (trade name “Bioalbumen”), the most abundant egg white protein, using micro-fermentation.
As with Perfect Day’s animal-free whey protein, Onego Bio’s animal-free egg proteins – which are produced by genetically modified microbes that feed on sugars in a fermentation tank – are designed to deliver the nutritional and functional benefits of animal proteins (Vital Proteins. identical to those found in eggs), without the environmental, ethical and safety concerns associated with the production of artificial eggs.
Oval albumin … the most prevalent protein in egg white
A start-up that grew out of VTT Technical Research Center in Finland and founded by Maya Eitkönen (CEO), Christopher Landowski (CTO) and José Joensuu (COO), Onego Bio is not the first player to enter the animal-free egg protein space, a pioneering Bay Area region, The EVERY Co, which uses yeast cells to make a variety of egg proteins.
However, Onego Bio propagates a different microorganism (a strain of Trichoderma fungi) to make egg proteins.
described by perfect dayCo-Founder and CEO Ryan Pandya as “A serious new player on the field,” Onego Bio aims to primarily target the US bakery and confectionery market, but is also eyeing the protein/fitness supplement market and considering moving into the consumer market with its own branded baking and cooking products.
Nth Biography: From Dynasty to Shelf
So why is Perfect Day entering the field of enterprise biology, and what kinds of support can Nth Bio provide for ambitious micro-brewing startups?
Perfect Day has already produced more animal-free whey protein in the first half of this year than in all of 2021, with the ability toThousands of metric tons“Starting next year with four commercial-scale facilities on three continents, while many space startups are still trying to take off, Ravi Gala, president of global commercial affairs, told FoodNavigator-USA.
“When we talk to a client or partner, they are often in awe of what we have been able to achieve in terms of being able to operate on a larger scale. We have a great team trying to create solutions from pressure to rack, this is the kind of service we want to provide [through nth Bio]And the From strain design to screening and fermentation to downstream process development, experiment and expansion.”
There are already experts in all of these individual sectors, he acknowledged, “But no one really connects them all, and if all the new startups in this field had to reinvent the wheel every time, we simply wouldn’t have the kind of impact that Perfect Day is trying to make.”
“If all the new startups in this field had to reinvent the wheel every time…”
As for the business model at Nth Bio, which also speaks “At least three to four other companies are in a very late stage of partnership agreements,”He said, it can be beautiful “Transactions are inherently dependent on what they need from a purely service point of view, but it can also be a more strategic partnership where we work hand in hand with a partner to bring an end product to the shelf.”
The Nth Bio facility in Salt Lake City, Utah is “Currently in the construction and commissioning phase. And the “The live broadcast is expected to start in the third quarter of 2023,” said Gala, who said he would have dedicated employees as well as two-hat-wearing key executives from Perfect Day..
“The primary focus of the facility will be on developing, piloting and scaling up critical processes as well as other resources and capabilities around stress design and screening.”
he added: “We started our journey in nutritional protein, but we can expand into other things like personal care, biology, materials, and we can support [companies working with] Yeast, Fungi and Bacteria [as host microorganisms]. “
“animal free” proteins
There is no official definition of “animal-free” protein – a term being tested by some startups in space – but it usually refers to products made with “real” animal proteins (whey, casein, collagen, egg yolk, myoglobin) that are produced Without animals, either by genetically modified microbes or genetically modified crops such as soybeans or peas.
Using synthetic biology, companies in this space are actively “programming” plants or single-celled organisms such as fungi and yeast to express animal proteins after feeding on sugars in fermentation tanks.
Final proteins are already familiar to the food industry (in GRAS’ design of animal-free whey protein, which is expressed by a genetically modified strain of filamentous fungi, for example, Perfect Day notes that”Identical to beta-lactoglobulin produced in cows.).
while her detractorsProponents argue that, using micro-fermentation to make animal-free dairy proteins and eggs, it offers the best of both worlds: more sustainableAnd ethical products that do not include industrial animal farming, but still provide nutrition and function for animal proteins.
While plant-based dairy and egg alternatives have improved significantly in recent years, they argue that animal proteins can provide certain technical or functional properties that can be difficult to replicate using plant proteins, from the melting and stretching of casein proteins in cheeses such as mozzarella and cheddar, or the properties of aeration, binding, coagulation, emulsification, foaming and whipping an eggwhiteness.
Nth Biography: From Dynasty to Shelf
Nth Bio can help with:
Evolution of the strain of microorganisms: Conducting stress improvement studies by improvisation and improving microbial fermentation.
Tools and IP authorization:Access to manufacturing equipment to maximize efficiency and improve affordability while protecting intellectual property and licensing technology mobility.
Fermentation services on a trial scale (1-2000 liters): Scale the key stages upstream and downstream, from proof of concept and process improvement to product specifications and requirements.
Downstream Process Development: Develop and implement product isolation, recovery and purification processes.
Regulatory approval strategy: “HeyOne of the main things a lot of our collaborators and partners are looking for is organizational support, as navigating these conversations at times can be very difficult, so we are investing some significant resources to help our partners in this regard,” ignorance said.
Image credit: Perfect Day
Founded in 2014, Berkeley-based Perfect Day supplies startups, emerging brands and multinational CPG cos (General Mills, Mar. Nestle) with animal-free beta-lactoglobulin, the primary protein in whey, as a supplier of b2b ingredients, with other products in the pipeline including alpha-lactalbumin (another whey protein) and casein proteins.
It has also developed its own brands for consumers across urgent companywhich makes a variety of CPG brands that publish animal-free whey protein including Brave Robot, Coolhaus (ice cream), Modern Kitchen (cream cheese) and California Performance Co (protein powders).
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