Diet modification can help women through menopause

Diet modification can help women through menopause

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Changing the diet can reduce unfavorable health changes associated with menopause such as controlling blood sugar and cholesterol levels.

Search published in eBioMedicine, From PREDICT, the largest study of its kind, it explores menopause affecting daily metabolism. The study included scientists from King’s, personal nutrition company ZOE, Harvard TH Chan School of Public Health, and Massachusetts General Hospital.

Menopause is defined as the point in time when a woman does not have a period of 12 months, and it usually occurs after the age of 45. This change in hormones means that women are more susceptible to changes in body composition, mood, sleep, inflammation, blood sugar control, and levels Cholesterol, which contributes to an increased risk of heart disease and many other metabolic health problems.

“Historically, menopause has been largely unstudied, and women have been underrepresented in health research, particularly with regard to diet and health. Our research shows that menopause is a time of significant metabolic disruption, which can have a significant impact on long-term health. These findings will help us provide simple but more personalized health and nutrition advice with greater efficacy to reduce the health burden of menopause,” says Dr. Sarah Perry from the College of Life Cycle and Population Sciences and study leader.

The researchers found major differences in inflammation and blood sugar levels after eating in postmenopausal women versus premenopausal women. The unfavorable effect of menopause on glycemic control, a major risk factor for cardiovascular disease and type 2 diabetes, was found even in women of similar age before and after menopause. This shows for the first time that this decline in glycemic control wasn’t just an inevitable part of aging.

Another new finding of this research is that the association between menopause, increased body fat, and inflammation is due in part to a poor diet and microbiome. This means that diet has a potential role in reducing these risk factors.

The research team also found that postmenopausal women consumed more dietary sugars and reported less sleep than premenopausal women. This increased the risk of type 1 and type 2 diabetes, obesity, and cardiovascular disease. These changes in diet and sleep, along with decreased physical activity reported in previous studies, are associated with decreased estrogen and may act in concert to increase the risk of weight gain over time.

The study also noted differences in the abundance of bacterial species between pre- and postmenopausal women, including pro-inflammatory and obese bacteria.

“The ZOE PREDICT study gives us an opportunity to study nutrition and health in thousands of people on an unprecedented scale, breadth and depth. Our insights help reveal the complex links between lifestyle, hormones, metabolism and health in a way that simply wasn’t possible before. Small changes in diet and lifestyle It has the potential to make a huge difference in how women manage their symptoms and improve this transmission,” says Kate Birmingham, first author on the research paper from the School of Life Cycle and Population Sciences.

“The good news is that what you eat may partially reduce the unfavorable health effects of menopause, either directly by reducing inflammation and hyperglycemia or indirectly by changing the microbiome to a more favorable composition,” said Dr.

Higher physical activity is associated with improved metabolic health risk factor in postmenopausal women

more information:
Kate M. Bermingham et al, Menopause is associated with postprandial metabolism, metabolic health and lifestyle: the ZOE PREDICT study, eBioMedicine (2022). DOI: 10.1016 / j.ebiom.2022.104303

Provided by King’s College London

the quote: Diet modification can help women through menopause (2022, October 18) Retrieved October 18, 2022 from

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