A nutritionally balanced whole food diet rich in fiber is good for gut health

A nutritionally balanced whole food diet rich in fiber is good for gut health

Effect of foods and nutrition on the gut microbiome. credit: Zhang Bing

The gut microbiome, or gut microbiota, also called a symbiosis, refers to the entire microbial community that inhabits the gastrointestinal tract of mammals, with the majority found in the colon. By generating a variety of metabolites, the gut microbiome interacts with the gut epithelium and the intestinal mucosal immune system to maintain gut homeostasis, thus forming a symbiotic relationship with the host.

Diet can upset gut balance by affecting the diversity, composition, and function of the gut microbiome. A balanced diet is critical for maintaining a healthy gut microbiome, integrity of the intestinal barrier, immune tolerance, and normal gut physiology, while an unbalanced diet, such as the typical Western diet, results in reduced diversity and dysplasia in the gut microbiome, which can It can lead to leaky gut and chronic inflammation, as seen in inflammatory bowel disease (IBD).

In a study published in International Journal of Molecular SciencesProfessor Zhang Ping of the Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences reviewed food and nutrition factors that affect gut health by influencing the interaction of the gut microbiome with the epithelium and the immune system of the gut mucosal.

The researcher discussed the effect of diet on the interaction of the gut immune system with the host in IBD.

According to the review, a nutritionally balanced, high-fiber diet not only provides the host with all the necessary nutrients, but also nourishes a healthy gut microbiome with high diversity and a well-balanced composition. Food choices must take the gut microbiome into account for overall gut health.

The researcher suggested that more research is needed to look at diet-microbe interactions in health and the molecular mechanisms of how nutritional components or nutritional status contribute to intestinal immune homeostasis.

“Understanding the impact of diet on the interaction of the gut microbiome and the host immune system will be useful in developing nutritional strategies to maintain gut health and restore a healthy microbiome in IBD,” said Zhang Ping.

The microbiome links diet to health

more information:
Bing Zhang, Effect of foods and nutrition on the gut microbiome and its implications for gut health, International Journal of Molecular Sciences (2022). DOI: 10.3390 / ijms23179588

Provided by the Chinese Academy of Sciences

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