A new study says that eating a lot of this may increase the risk of developing liver cancer - better life

A new study says that eating a lot of this may increase the risk of developing liver cancer – better life

Increasingly, researchers are demystifying the many ways the microbiome affects our broader health. “Gut health is really important,” says a registered dietitian Kristen KirkpatrickRD, tells the Cleveland Clinic. “There is a lot of interest and research Microbiome and gut health Now that experts often refer to it as the “second brain,” she says.

Now, new research suggests that eating too much of one food in particular — a vital substance found in a lot of the foods you probably already eat — can cause a significant risk of liver cancer in some, despite a broader reputation as a harbinger of health. Read on to find out which food item can increase your risk of liver cancer by 40 percent, and why only some people have this problem.

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Your gut microbiome It is made up of trillions of microorganisms that live in your stomach and intestines. “In a healthy person, these ‘insects’ coexist peacefully, with the largest numbers present in the small and large intestines but also throughout the body,” explains Harvard T.H. Chan School of Public Health, noting that these facilitate daily life. The working day of the human body. They noted, “The microbiome is made up of both beneficial and potentially harmful microbes. Most are symbiotic (where both the human body and microbes benefit) and some, in smaller numbers, are pathogenic (disease-promoting).

Now, some researchers say that a certain biomaterial Affects the risk of liver cancer By changing gut health – and arguing that this fits with their broader understanding of how gut health affects overall health. “We’ve been working for a long time on the idea that all diseases start in the gut,” he said. Matam Vijay KumarPh.D., study author and professor in the Department of Physiology and Pharmacology in the College of Medicine and Life Sciences and senior author of the paper.

Read next: Having this type of blood increases your risk of pancreatic cancer by 70 percent.

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According to the new study, which was conducted on experimental mice, individuals who eat rich diets Refined fibers like insulin You may be at increased risk of developing liver cancer. Researchers note that one in 10 healthy animals Liver cancer progression After eating a diet containing insulin.

“This was very surprising, given how rare there is to be liver cancer in mice,” said Vijay Kumar. direct science. He says that although fiber is a healthy addition to most people’s diets, “the results raised real questions about the potential risks.” Some refined fibers. “Foods that contain inulin include whole wheat, and some fruits and vegetables, including asparagus, bananas, and garlic.

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During their study, the researchers realized that mice that developed liver cancer all had one thing in common: They had an excess of bile acids in their blood due to a previously unnoticed birth defect known as a portal shunt. . In fact, 100 percent of the mice with this abnormality developed metastasis, while none of the mice with low bile acids had this problem while being fed the same diet.

Researchers believe this occurred due to an inflammatory response that can be generated when blood leaves the intestine. Under normal circumstances, this blood goes to the liver, where it is filtered before returning to the rest of the body. However, when a mouse has a portal shunt, blood from the gut will bypass the liver and end up back in the body’s general blood supply while still containing a high concentration of microbial products. These stimulate an inflammatory immune response, which can eventually lead to cancer.

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The main takeaway, according to the researchers, is that from one individual to another, our bodies process nutrients differently. According to additional data they collected from human blood serum samples, men who had the highest levels of bile acid in their blood and consumed a high amount of fiber had a 40 percent increased risk of developing liver cancer. However, the men with the lowest levels of bile acid in their blood and those with a high overall fiber intake saw a 29 percent reduced risk of liver cancer.

The study authors say these findings support the need for more blood bile acid level testing. Those who are aware that they have abnormally high levels of bile acids should consider changing their diet with the help of a doctor or dietitian. “All fiber is not created equal, and all fiber is not good for everyone in general. People with liver problems associated with excess bile acids should be careful about refined, fermentable fibers,” Bing San YeohHe is a postdoctoral fellow and first author of the new paper direct science. “If you have a leaky liver, you have to be careful about what you eat, because what you eat will be treated differently.”

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